B.Sc. (Nursing) DEGREE EXAMINATION
First Semester
(Modified Regulation)
Pharmacology
Select the most appropriate response.
1. Streptmycin sulphate is not absorbed orally because it is
- Degraded by gastrointestinal enzymes
- Destroyed by gastric acid
- Highly ionized at a wide range of pH values
- Insoluble in water
2. The aminoglycoside antibiotic which is distinguished by its resistance to bacterial aminoglycoside inactivating enzyme is
- Kanamycin
- Sisomycin
- Amikacin
- Tobramycin
3. An aminoglycoside antibiotic should not be used concurrently with the following drugs
- Ampicillin
- Vancomycin
- Ciprofloxacin
- Rifampicin
4. All of the following statements regarding pentamidine isethionate are true except
- It is indicated for threatment or prophylaxis of infection due to Pneumocystis carini
- It may be administered intramuscularily, intravenously or by inhalation
- It has no clinically significant effect on serum glycose
- It is effective in the treatment of leishmaniasis
5. Prolonged oral therapy with the following antibiotic can damage intestinal villi resulting in steatorrhoea and loose motions
- Ampicillin
- Tetracycline
- Neomycin
- Nystatin
6. Hepatitis with cholestatic jaundice occurs most frequently as an adverse reaction to the following preparation of erythromycin
- Erythromycin base
- Erythromycin stearate
- Erythromycin estolate
- Erythromycin ethylsuccinate
7. The following antibiotic is a first line drug for tratment of Mycobacterium avium complex infection in AIDS patients
- Clindamycin
- Clarithromycin
- Roxithromycin
- Erythromycin
8. Roxithromycin has the following advantages over erythromycin except
- It is more effective in whooping cough
- It causes less gastric irritation
- It has longer plasma half-life
- It is unlikely to precipitate theophylline toxicity
9. The highest incidence of antibiotic associated pseudo membranous enterocolitis has been noted with the use of
- Ampicillin
- Chloramphenicol
- vancomycin
- Clindamcin
10. The drug of choice for treatment of methicillin resistant Staphylococcus aureus infection is
- Cloxacillin
- Vancomycin
- Erythromycin
- Amikacin